2 DOSAGE AND ADMINISTRATION

For more information about this side effect, see the “Sildenafil: Side effect specifics” section below. Use of the term “female” and “male” in this article refers to sex assigned at birth.

What are Sildenafil Tablets

As with other drugs, sildenafil can cause side effects (adverse effects). It’s typically taken as a long-term treatment. Read on to learn about potential common, mild, and serious side effects. For a general overview of sildenafil, including details about its uses, refer to this article. Your doctor can also tell you more about sildenafil.

Patient resources

Sildenafil can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. These are just a few of the more common side effects reported by people who took sildenafil in clinical trials:* * To learn more about the clinical trials of sildenafil, refer to the drug’s prescribing information for erectile dysfunction and pulmonary arterial hypertension. † For more information about this side effect, see “Sildenafil: Side effect specifics” below. It’s possible to develop long-term side effects from sildenafil treatment. In clinical trials,* long-term side effects, such as vision loss and hearing loss,† occurred at any time during treatment. However, the exact reason why these side effects occurred is not fully known. If you have any sudden changes in your vision or hearing, talk with your doctor right away. Also talk with them if you’re concerned about long-term side effects with sildenafil treatment.

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* To learn more about the clinical trials of sildenafil, refer to the drug’s prescribing information for erectile dysfunction and pulmonary arterial hypertension.

Side Effects

Optum Perks is owned by RVO Health. By clicking on this link, we may receive a commission. Mild side effects can occur with sildenafil use. This list doesn’t include all possible mild side effects of the drug. For more information, you can refer to sildenafil’s prescribing information for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH).

Frequently asked questions

Mild side effects that have been reported with sildenafil include: These side effects may be temporary, lasting a few days to weeks. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you develop a side effect while taking sildenafil and want to tell the FDA about it, visit MedWatch. * For more information about this side effect, see “Sildenafil: Side effect specifics” below. † An allergic reaction is possible after taking sildenafil. † For more details about these side effects, including their symptoms, see the “Sildenafil: Serious side over the counter drugs containing sildenafil effects” section above. Learn more about some of the side effects that sildenafil may cause.

• Common side effects include headache, flushing, and dizziness.
• Always follow your doctor's dosage instructions carefully.
• Avoid alcohol while taking sildenafil to reduce risks.
• Store tablets in a cool, dry place away from children.

To find out how often side effects occurred in clinical trials, see the drug’s prescribing information for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). However, this side effect was rare in clinical trials. * Sildenafil is a vasodilator, meaning it widens the blood vessels and makes it easier for blood to flow. When this happens, your blood pressure may drop. This is because your heart doesn’t have to work as hard to move blood around your body.

• Sildenafil 25 mg tablets are used to treat erectile dysfunction.
• They work by increasing blood flow to the penis.
• Typically taken 30-60 minutes before sexual activity.
• Do not exceed one dose per day to avoid side effects.

Signs and symptoms of low blood pressure include tiredness, lightheadedness, or blurry vision. They may also include nausea, dizziness, fainting, and confusion.

In case of emergency/overdose

However, this side effect was rarely reported in clinical trials of sildenafil for ED and PAH. To learn more, see the “Sildenafil: Side effect specifics” section below. The list below may not include all possible serious side effects of the drug. If you develop serious side effects while taking sildenafil, call your doctor right away. If the side effects seem life threatening or you think you’re having a medical emergency, immediately call 911 or your local emergency number.

Pregnancy Categories

Serious side effects that have been reported and their symptoms include: Symptoms can include:tinnitus (ringing in your ear)dizzinessdecrease in hearing Symptoms can include:trouble seeing in either eyeblurry visionseeing eye floaters * To learn more about this side effect, see the “Sildenafil: Side effect specifics” section below. Sildenafil is not approved by the Food and Drug Administration (FDA) for use in children. In clinical trials, children who sildenafil citrate tablet were given sildenafil long term to treat pulmonary arterial hypertension had an increased risk of fatality. However, your child’s doctor may recommend taking sildenafil off-label in some cases. (With off-label use, a doctor prescribes an FDA-approved drug for a purpose other than what it’s approved for.) Talk with your child’s doctor to determine if sildenafil is right for your child. Low blood pressure can be mild or severe depending on how much your blood pressure drops. You may have an increased risk of severe low blood pressure if you: already take drugs to lower your blood pressure have a blood pressure less than 90/50 before taking sildenafil If you take blood pressure drugs during sildenafil treatment, your doctor will recommend monitoring your blood pressure regularly. If you notice any signs or symptoms of low blood pressure while taking sildenafil, talk with your doctor. They’ll review your symptoms and other medications to make sure it’s safe for you to keep taking the drug. * To learn more about the clinical trials of sildenafil, refer to the drug’s prescribing information for ED and PAH.

Detection in biological fluids

In clinical trials,* a similar number of people reported certain side effects with both 50-mg and 100-mg doses. These side effects included mild to moderate headaches, flushing, and back pain. However, people taking the 100-mg dose had an increased risk of upset stomach, vision changes, and runny nose. If you have questions about the side effects of your prescribed sildenafil dose, talk with your doctor or pharmacist. * To learn more about the clinical trials of sildenafil, refer to the drug’s prescribing information for erectile dysfunction and pulmonary arterial hypertension (PAH). Headache is a possible side effect while taking sildenafil. Headaches were common and typically mild in clinical trials of the drug.* If you start to experience headaches often or if they affect your daily life, talk with your doctor. They may recommend lifestyle changes, such as more rest to help ease your headache. Your doctor may also recommend pain medications to help treat your headache.

Patient Group	Recommended Starting Dose	Max Dose	Timing	Special Considerations
Adult Men for ED	25 mg, 1 hour before use	50 mg	1 hour before sexual activity	Do not exceed once daily
Patients with Liver Disease	25 mg, after medical consultation	25 mg	Adjusted as per doctor	Monitor for side effects
Elderly Patients	25 mg, as per physician's advice	25 mg	Take with food or without	Increased sensitivity possible

These may include ibuprofen (Advil, Motrin) or acetaminophen (Tylenol). Severe cardiovascular problems may occur during sildenafil treatment. This side effect was reported* in people taking sildenafil for ED after the drug was approved. Cardiovascular problems, such as heart attack, stroke, irregular heartbeat, lung bleeding, and brain bleeding were rarely reported.

5.5 Hypotension when Co-administered with Alpha-blockers or Anti-hypertensives

Some of the most common issues include premature, delayed, or retrograde ejaculation. Your pelvic floor is a lot like plumbing in your home: you never really think about it unless something goes wrong. When you think of male sexual dysfunction, concerns like erectile dysfunction (ED) or premature ejaculation (PE) probably come to mind first. But there’s another sex-related issue that’s more common in men than you might expect: difficulty orgasming. Sildenafil (Revatio, Viagra) is a generic prescription medication used to treat erectile dysfunction and pulmonary arterial hypertension in adults.

Sildenafil Oral Film for ED

Sildenafil, which is also called sildenafil citrate, comes as an oral tablet. The drug also comes as an oral liquid suspension and IV infusion. However, this article does not cover these forms. It only covers the side effects of sildenafil oral tablets. If you’d like to learn more about these forms, talk with your doctor. Many of these reported side effects occurred during or shortly after sexual activity. Most of the people who experienced cardiovascular problems during sildenafil treatment already had other heart-related conditions. So it’s unknown if sildenafil was the direct cause of these side effects.

Are erectile dysfunction medicines safe?

No, sildenafil isn’t known to cause different side effects in females. * Sildenafil is approved to treat PAH in most adults, including females. If you’re female and concerned about side effects with sildenafil, talk with your doctor. Note: If you’re male, priapism may occur during sildenafil treatment. With priapism, you experience a continued (4 hours or longer) erection that’s often painful. They may be due to other factors, such as preexisting heart disease, sexual activity, or a combination of these factors.

Frequently asked questions

They can help compare the risks and benefits of the drug. Sildenafil oral tablets come in different strengths: 20 milligrams (mg), 25 mg, 50 mg, and 100 mg. The dosage you’re prescribed will depend on what condition you’re taking sildenafil for. It also depends on how the dosage is working for you. You can experience mild or severe side effects from sildenafil with any dosage.

Sildenafil: the science

However, you may have an increased risk of side effects with higher dosages. If you start to experience side effects that become bothersome or severe while taking sildenafil, talk with your doctor. Here are some frequently asked questions about the drug’s side effects and their answers. No, there aren’t any reviews from people who’ve taken 50-milligram (mg) or 100-mg sildenafil tablets. However, you may experience mild or severe side effects from sildenafil with any prescribed dose. Before you start sildenafil treatment, be sure to tell your doctor if you have any heart conditions. Depending on your heart health, sildenafil may not be safe for you to take.

Condition	Patient Group	Recommended Dose	Notes
Erectile Dysfunction	Men over 18	25-50 mg	As needed before activity
Pulmonary Arterial Hypertension	Adults with PAH	25 mg	Under medical supervision
Altitude Sickness Prevention	High altitude travelers	25 mg	Off-label use

Your doctor can review the risks and benefits of taking sildenafil to determine the right treatment plan for you. If you’re interested in having sex while taking sildenafil for ED or PAH, talk with your doctor before starting treatment. It’s important to talk with your doctor about your heart health before having sex.