However, there are some side effects and drug interactions that you should be aware of before taking any medication for ED.

Age is a major risk factor due to increased vascular issues and declining testosterone.
Diabetes mellitus damages nerves and blood vessels, a leading organic cause of ED.
Hypertension and atherosclerosis narrow penile arteries, restricting blood flow.
Metabolic syndrome (obesity, high blood pressure, insulin resistance) strongly correlates with ED.
Radical prostatectomy or other pelvic surgeries can damage nerves controlling erections.
Spinal cord injuries or neurological disorders (MS, Parkinson's) disrupt nerve signals.
Hormonal disorders: Low testosterone, high prolactin, or thyroid problems.
Certain prescription medications: Antihypertensives, antidepressants, antipsychotics, diuretics.

These side-effect rates can differ from one drug to another, meaning one may be a more effective option for you than its alternatives depending on your personal needs and health profile.

Lifestyle Changes That Support Erectile Function

No matter what causes erectile dysfunction, it can be a source of stress for you and your partner. Here are some steps you can take: It's common to have erection problems sometimes. Thinking you'll have it again or that it's a sign of something wrong with you can cause stress. Your partner might think not being able to have an erection is a sign that you have less desire for sex. Assure your partner that this isn't true.

Vacuum erectile device

Treatment can work better for you when you involve your partner. Don't ignore stress, anxiety or other mental health concerns. Talk to your healthcare professional or a mental health professional to deal with these issues. You're likely to start by seeing your main healthcare professional. Your healthcare professional may send you to a specialist. Below, we’ve explained how ED medications work, their potential side effects, and other key safety data that you should be aware of before using any medication to treat ED. Erectile dysfunction is a common form of sexual dysfunction that affects an estimated 30 to 50 million men in the United States alone. Studies estimate that as many as 40 percent of all men will deal with some level of erectile dysfunction by the age of 40 — and that rate only increases with age.

Viagra (Sildenafil): The most well-known ED pill that increases blood flow to the penis for reliable erections.
Cialis (Tadalafil): Offers long-lasting effects up to 36 hours, suitable for spontaneous sexual activity.
Levitra (Vardenafil): Works quickly and lasts around 4-5 hours, effective for men with diabetes-related ED.
Stendra (Avanafil): Rapid onset within 15 minutes, with fewer side effects, ideal for on-demand use.
Kamagra: An affordable alternative to branded pills, containing Sildenafil, but quality varies.
Spedra: Fast-acting ED medication with quick relief, effective for those needing urgent results.
Cenforce: Generic Sildenafil option, often at a lower price, with similar effectiveness.
Vidalista (Tadalafil): Suitable for daily or as-needed use, with extended duration.
Malegra: Generic Sildenafil-based pills, popular for affordability and effectiveness.
Tadalista: Tadalafil-based, used for ED and prostate issues, with long duration effects.
Eriacta: Generic Sildenafil tablets, trusted as a cost-effective ED solution.

But certain treatments can help manage the condition’s key symptoms.

Product Name	Rating (out of 5)	Number of Reviews	Price Range	Notes
Viagra	4.5	10,000+	$30-$50 per pill	Well-known, proven efficacy
Cialis	4.6	8,500+	$35-$70 per pill	Long-lasting effect
Levitra	4.4	6,000+	$30-$60 per pill	Quick onset
Stendra	4.3	4,200+	$40-$75 per pill	Fast-acting

Erectile dysfunction medication has been around since the late 1990s, when the FDA approved Viagra as the first pill for treating ED (here is a guide on where to buy Viagra). Currently, there are four FDA-approved oral medications for ED: The active ingredient in Viagra, sildenafil, is the most well-known medication for erectile dysfunction.

Product	Dosage	Quantity + Bonus	Price
Viagra Generic	25mg	120 + 6 Pills	125.56€ 119.58€
Viagra Generic	150mg	10 Pills	36.73€ 34.98€
Cialis Generic	20mg	10 Pills	31.49€ 29.99€
Levitra Generic	10mg	180 + 10 Pills	246.74€ 234.99€
Viagra Generic	200mg	120 + 8 Pills	204.80€ 195.05€
Cialis Original	20mg	120 + 8 Pills	497.29€ 473.61€
Kamagra Gold	50 mg	60 + 4 Pills	171.14€ 162.99€
Kamagra Soft Tabs	100 mg	12 Pills	57.55€ 54.81€
Kamagra Polo	100mg	12 Pills	60.21€ 57.34€
Kamagra 100 mg	100 mg	20 Pills	86.09€ 81.99€
Cialis Professional	20mg	270 + 6 Pills	623.07€ 593.40€
Viagra Soft Tabs	100mg	30 + 4 Pills	83.06€ 79.10€
Viagra Generic	200mg	360 + 10 Pills	481.98€ 459.03€
Cialis Generic	10mg	180 + 8 Pills	236.88€ 225.60€

It’s designed for use at least one hour before sex and works for about four hours per dose. Sildenafil is available as the brand-name Viagra and as a generic version. It’s a popular choice that works well for most men affected by ED.

How do erection pills work?

But you can bend it away from the body for sex and toward the body when you don't want it to show. Healthcare professionals don't often suggest penile implants until you've tried other erectile dysfunction treatments first. People who have tried other therapies without success tend to be happy with their implants. As with any surgery, there's a risk of complications, such as infection. Maybe stress, anxiety or depression causes your erectile dysfunction or the condition makes stress and issues with your partner.

5. Penile implant

Then your healthcare professional may suggest that you, or you and your partner, see a counselor. There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. We use the data you provide to deliver you the content you requested. The active ingredient in Viagra, sildenafil, is the most well-known medication for erectile dysfunction.

Product Name	Main Benefits	Active Ingredients	Cautions	Price Range
Cialis	Long-lasting action	Tadalafil	May interact with nitrates	$35-$70 per pill
Levitra	Reliable effects	Vardenafil	Possible dizziness	$30-$60
Super P-Force	Combines Sildenafil + Dapoxetine	Faster onset	Use as prescribed	$40-$70

The active ingredient in Cialis®, tadalafil, is an ED drug that offers relief for up to 36 hours per dose.

Initial consultation typically involves a detailed medical and sexual history.
Follow-up appointments assess medication effectiveness and adjust treatment plans.
Combination therapy (e.g., oral pill + injection) may be used for difficult cases.
Treatment goals are individualized: restoration of satisfactory sexual intercourse.
Partner involvement in consultations is often encouraged for better outcomes.
Monitoring for side effects and drug interactions is an ongoing process.
Treatment may evolve as health conditions change or new therapies become available.
A good doctor-patient relationship is key to successful long-term management.

This long duration of action has earned it the nickname, the “weekend pill.” Tadalafil is available as the brand-name Cialis and as a generic medication. It can be used as needed before sexual activity or taken daily at a reduced dosage to provide ongoing ED relief. The active ingredient in Levitra®, vardenafil, works similarly to sildenafil but has a slightly longer half-life. This means it remains active in the body for longer. It’s only available as a generic medication. The active ingredient in Stendra®, avanafil, is a second-generation medication for ED. It’s more selective in its effects than older ED drugs and starts working in as little as 15 minutes. It’s also less likely to cause some side effects. Currently, it’s only available as the brand-name medication, with no generic option available for sale. Other ED medications exist besides these oral ones. Alprostadil (Caverject®) is an FDA-approved medication for ED that can be injected or used inside the urethra. Compounded medications like BiMix, TriMix, and QuadMix can also be used for ED and are given by injection or in the urethra—but know that compounded medications are not FDA-approved. All four of the oral medications listed above belong to a class of drugs called PDE5 inhibitors.

Who Should Avoid Erection Pills?

To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices. You may opt out of email communications at any time by clicking on the unsubscribe link in the email. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Please, try again in a couple of minutes For many people, lifestyle choices cause erectile dysfunction or make it worse.

Can you permanently get rid of ED?

Here are some tips that might help: If you have trouble quitting, get help. Try nicotine replacement, such as over-the-counter gum or lozenges. Or ask your healthcare professional about a prescription medicine that can help you quit. Being overweight can cause erectile dysfunction or make it worse. Exercise can help with underlying conditions that play a part in erectile dysfunction by easing stress, helping you lose weight and increasing blood flow. These medications work by inhibiting the effects of the enzyme phosphodiesterase type 5 (PDE5).

The bottom line

National Center for Complimentary and Integrative Health. Safety is a key factor to consider before using any medication, and treatments for erectile dysfunction (ED) are no exception. Luckily, ED is a treatable issue with several well-known options, such as sildenafil (the active ingredient in Viagra®), tadalafil (Cialis®), and newer ED treatments, such as avanafil (Stendra®). The United States Food and Drug Administration (FDA) approves all of these medications. All of the FDA-approved ED medications on the market right now are safe for most men to use regularly. This enzyme breaks down a signaling molecule called cyclic guanosine monophosphate (cGMP), which plays a key role in relaxing smooth muscles and regulating blood flow to the erectile tissue of the penis. When cGMP is active, it triggers the release of nitric oxide, which causes blood vessels to widen. This allows blood to flow into the penis, expanding the corpora cavernosa and leading to a firmer, fuller erection. By breaking down cGMP, PDE5 stops the signal that allows blood vessels to relax, limiting blood flow and making erections harder to achieve.

What Is Erectile Dysfunction?

Are there any brochures or other printed material that I can have? Be sure to ask all the questions you have. Your healthcare professional is likely to ask questions, such as: What other health concerns or ongoing conditions do you have? Do your erectile problems happen sometimes, often or all the time? Do you want sex less than you used to?

3. Urethral suppository

Do you get erections during masturbation, with a partner or while you sleep? Are you anxious, depressed or under stress? What seems to help with your erectile dysfunction? What seems to make your erectile dysfunction worse? Epidemiology and etiologies of male sexual dysfunction. PDE5 inhibitors work by blocking this enzyme, allowing cGMP levels to rise. As a result, blood vessels in the penis can dilate more fully, making it easier to get and maintain an erection.

Which Erection Pill Is Best for You?

This could be a doctor who specializes in male genital problems, called a urologist, or a doctor who specializes in the hormonal systems, called an endocrinologist. Here's some information to help you get ready for your appointment. Take your partner with you, if you can. Your partner can help inform your healthcare professional and remember the information you get. Your symptoms, including any that may not seem linked to erectile dysfunction, and when they began.

Effective treatments, trusted by over 500,000 men

Key personal information, including any major stresses or recent life changes. All medicines, vitamins, herbal remedies and supplements super p force online you take, including dosages. For erectile dysfunction, some questions to ask include: What's the most likely cause of my erection troubles? Is my erectile dysfunction most likely to go away or to last? What are the treatments and which do you suggest? The other treatment options for ED work through a variety of processes, including dilating the blood vessels, stimulating the nerves of the penis, and pulling more blood into the penis with negative pressure.

Brand Name	Main Ingredients	Effect Duration	Notes	Age Restrictions
VigRX Plus	Horny goat weed, Muira Puama	4-6 hours	Herbal supplement	18+
Max Performer	L-Arginine, ginseng	2-3 hours	Natural ingredients	18+
ProSolution	Tribulus terrestris	4-5 hours	Available online	18+

However, these options don’t treat the psychological side of ED, meaning they won’t help you to feel more sexually stimulated or increase your libido.

When oral medications might not be safe

Get treatment for alcohol or drug overuse. Drinking too much or taking certain illicit drugs can make erectile dysfunction worse. And overuse can cause long-term health problems that make erectile dysfunction worse. Think about couples counseling for help working through problems with your partner. Before using any supplement, check with your healthcare professional to make sure it's safe for you, especially if you have ongoing health conditions.

Which Medication Will Work Best for My ED?

Some alternative products that claim to work for erectile dysfunction can cause harm. The Food and Drug Administration has issued warnings about some types of "herbal viagra" because they may have harmful ingredients not listed on the package. Or they might have been tainted while being made. Some of these supplements can interact with prescription medicines and cause very low blood pressure. These products are a special danger for anyone who takes nitrates. And, after all, erectile dysfunction can certainly have physical and psychological causes.

Online Consultation Platforms: Telemedicine services for personalized ED treatment advice.
Herbal Clinics: Specialized clinics offering natural ED solutions.
Fitness & Diet Tips: Lifestyle changes to naturally improve erectile health.
Stress Reduction Techniques: Mindfulness, meditation to reduce performance anxiety.
Sleep Optimization: Better sleep improves overall blood flow and libido.
Regular Exercise: Improves vascular health supporting erections.
Balanced Diet: Rich in antioxidants and nutrients supporting sexual function.
Alcohol & Smoking Cessation: Reduces factors that impair blood flow.
Weight Loss Programs: Reduce obesity-related ED risk factors.
Hydration & Supplements: Keep the body well-hydrated to support overall health.
Sexual Therapy: Counseling to treat psychological causes of ED.

Physical causes include heart and blood vessel disease, diabetes, atherosclerosis (clogged arteries), and damage to the penis or surrounding tissue, which can affect nerve function and blood flow.

Oral Medications for ED – An Overview